The Clozapine Clinic provides monitoring, assessments and aims to better understand the reason why some people with schizophrenia improve with this medication and why others do not achieve the same level of improvement. 

People diagnosed with schizophrenia can get free of psychotic symptoms, can have a full-time job and can have an active social and family life.

People diagnosed with schizophrenia are often presented as suffering with a chronic, invalidating and disabling hopeless mental disorder. However, reality shows that outcome in chronic schizophrenia is far more colourful than this pessimistic picture. A significant group of subjects has a successful recovery history to tell, most of them carrying a perfectly achieving life.

Some of them, but not all, are treated with clozapine, an atypical antipsychotic medication. This particular medication has shown superiority compared to the other antipsychotics for the treatment of the resistant symptoms of psychosis in schizophrenia, but also improves negative symptoms and reduces the risk of suicide. However, due to potential effects to the blood white cells, it needs regular monitoring - generally once per month.

The Clozapine Clinic, whose lead clinician Dr Emilio Fernandez was recently honoured, by provides this monitoring, but also offers other assessments and opportunities. The Clozapine Clinic is part of the rehabilitation and recovery pathway and works within the rehabilitation and recovery teams.

A key part of the clinic is the link with academics, as we aim to better understand the reason why so many people improve with this medication and why others do not achieve the same level of improvement. 

How can this service help you?

At the Clozapine Cinic, we do mandatory weekly/monthly blood monitoring. We also check your physical health every three months, assessing your weight, waist perimeter and ask you for all possible side effects that clozapine may produce. If necessary, we can also check how much clozapine is getting to your blood, which will allows us to treat you with the minimum dose necessary to avoid side effects.

We also make sure you have been seen by your GP regularly - at least once a year you should be getting a full physical check at your surgery.

In the research area, the team is involved in several studies, both locally and in collaboration with other centres in the UK. So, if you would like to help us to understand how clozapine works and why is effective in some people, please let us know or visit the research webpage of our team.

How do I access this service?

If you are taking clozapine, you are probably already seen at the Clozapine Clinic, either in Cambridge, Huntingdon or Peterborough.

If you are diagnosed with schizophrenia and you are still experiencing symptoms of psychosis or negative symptoms, you might want to discuss with your consultant whether a trial with clozapine might be useful.

Where is it?

Cambridge (Wednesdays)

Tenison Road
Cambridge
Phone: 01223 516926 (reception); 01223 516968 (main clinic)

Peterborough (Wednesdays)

Cavell Centre
Bretton Gate
Peterborough
PE3 9GZ



Huntingdon (Tuesdays)

Newtown Centre
Nursery Road
Huntingdon
PE29 3RJ

The page was last updated on 01 March 2017 by rmitchell.

Cambridgeshire and Peterborough NHS Foundation Trust
Elizabeth House, Fulbourn Hospital
Cambridge, CB21 5EF

T 01223 219400 (open 8:30am to 5pm)
F 01480 398501

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